BDBM469166 N-[6-(1,5-dimethyl-6-oxopyridin-3-yl)-1-[(2R)-1- methoxypropan-2-yl]-2-methylbenzimidazol-4- yl]methanesulfonamide::US10807982, Example 46

SMILES COC[C@@H](C)n1c(C)nc2c(NS(C)(=O)=O)cc(cc12)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=NRNTWQJZJADSJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469166   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM469166(N-[6-(1,5-dimethyl-6-oxopyridin-3-yl)-1-[(2R)-1- m...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
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Date in BDB:
6/11/2021
Entry Details
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