BDBM469164 Step 1: 6-bromo-2-methyl-4-nitro-1-(1-phenylethyl)benzimidazole::US10807982, Example 44::US10807982, Example 45

SMILES CC(c1ccccc1)n1c(C)nc2c(NS(C)(=O)=O)cc(cc12)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=IPDVTHZWXBGFMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 469164   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM469164(Step 1: 6-bromo-2-methyl-4-nitro-1-(1-phenylethyl)...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM469164(Step 1: 6-bromo-2-methyl-4-nitro-1-(1-phenylethyl)...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent