BDBM469150 4-[6-(cyclopropylmethoxy)-3-ethylsulfonyl-1- methylindazol-5-yl]-2-methylisoquinolin-1-one::US10807982, Example 30

SMILES CCS(=O)(=O)c1nn(C)c2cc(OCC3CC3)c(cc12)-c1cn(C)c(=O)c2ccccc12

InChI Key InChIKey=AWTVHDWTTKQFKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 469150   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM469150(4-[6-(cyclopropylmethoxy)-3-ethylsulfonyl-1- methy...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BREM was cloned, expr...More data for this Ligand-Target Pair
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Date in BDB:
6/11/2021
Entry Details
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