BDBM468962 US10807966, Compound 39

SMILES COc1cccc(CNC(=O)c2cc3ccc(nc3s2)-c2ccncc2)c1

InChI Key InChIKey=TXBFBOHWKUHOLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468962   

TargetRho-associated protein kinase 2(Human)
Translational Drug Development

US Patent
LigandPNGBDBM468962(US10807966, Compound 39)
Affinity DataIC50: 17.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Translational Drug Development

US Patent
LigandPNGBDBM468962(US10807966, Compound 39)
Affinity DataIC50: 65.1nMAssay Description:The following assay protocol is for measuring the phosphorylation of a peptide substrate (FAM-KKLRRTLSVA-OH wherein FAM is carboxyfluorescein). The p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent