BDBM468566 US10806794, Compound mPEG7-amide-Tipranavir

SMILES CCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(c2)N(CCOCCOCCOCCOCCOCCOCCOC)S(=O)(=O)c2ccc(cn2)C(F)(F)F)C(=O)O1

InChI Key InChIKey=NGFPBWVYUHBTNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468566   

TargetHIV-1 protease(Human immunodeficiency virus)
Nektar Therapeutics

US Patent
LigandPNGBDBM468566(US10806794, Compound mPEG7-amide-Tipranavir)
Affinity DataIC50: 12.2nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent