BDBM468426 US10806785, Example 70::cis-4-((2-((2,2'-dichloro-3'- (5-ethyl-1-methyl-4,5,6,7- tetrahydro-1H-imidazo[4,5- c]pyridine-2-carboxamido)- [1,1'-biphenyl]-3- yl)carbamoyl)-1-methyl- 1,4,6,7-tetrahydro-5H- imidazo[4,5-c]pyridin-5- yl)methyl)cyclohexane-1- carboxylic acid

SMILES CCN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(C[C@H]5CC[C@H](CC5)C(O)=O)CCc4n3C)c1Cl)n2C

InChI Key InChIKey=FMULGIYMHMVFKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468426   

LigandPNGBDBM468426(US10806785, Example 70 | cis-4-((2-((2,2'-dichloro...)
Affinity DataIC50: 0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent