BDBM468352 US10806720, Compound 1037::US11230523, Compound 1037::US11648234, Compound 1037

SMILES C[C@](O)(CBr)C(=O)Nc1ccc(nc1)C#N

InChI Key InChIKey=RZEYAXYJUPCYIO-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 468352   

TargetAndrogen receptor(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468352(US10806720, Compound 1037 | US11230523, Compound 1...)
Affinity DataIC50: 350nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468352(US10806720, Compound 1037 | US11230523, Compound 1...)
Affinity DataIC50: 350nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent

TargetAndrogen receptor(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468352(US10806720, Compound 1037 | US11230523, Compound 1...)
Affinity DataKi:  4.55E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
Go to US Patent

TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468352(US10806720, Compound 1037 | US11230523, Compound 1...)
Affinity DataKi:  4.55E+3nMAssay Description:hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD was combin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
Go to US Patent

TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468352(US10806720, Compound 1037 | US11230523, Compound 1...)
Affinity DataKi:  4.55E+3nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
Go to US Patent