BDBM467355 N-((3R,5R)-1-Acryloyl-5-hydroxypiperidin-3-yl)-5-(2-methyl-4- phenoxyphenyl)-4-oxo-4,5-dihydro-3H-1-thia-3,5,8- triazaacenaphthylene-2-carboxamide;::US10800792, Example 6

SMILES CC(C)(C)OC(=O)N1CC[C@@H](NC(=O)c2sc3nccc4n(-c5ccc(Oc6ccccc6)cc5)c(=O)[nH]c2c34)[C@H](O)C1

InChI Key InChIKey=WSTDTTGZAGCAFG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 467355   

TargetTyrosine-protein kinase BTK(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM467355(N-((3R,5R)-1-Acryloyl-5-hydroxypiperidin-3-yl)-5-(...)
Affinity DataIC50: 12.6nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent