BDBM46732 2-(4-chlorophenyl)-5-fluoranyl-1,2-benzothiazol-3-one::2-(4-chlorophenyl)-5-fluoro-1,2-benzothiazol-3-one::MLS-0390975.0001::cid_25241618

SMILES Fc1ccc2sn(-c3ccc(Cl)cc3)c(=O)c2c1

InChI Key InChIKey=YXWIDPAKPFDLLL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 46732   

TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46732(cid_25241618 | 2-(4-chlorophenyl)-5-fluoranyl-1,2-...)
Affinity DataIC50: 1.77E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetGlucose-6-phosphate 1-dehydrogenase(Leuconostoc mesenteroides)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM46732(cid_25241618 | 2-(4-chlorophenyl)-5-fluoranyl-1,2-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Excerpt from MH082340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African sleep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetPhosphotransferase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM46732(cid_25241618 | 2-(4-chlorophenyl)-5-fluoranyl-1,2-...)
Affinity DataIC50: 3.01E+3nMAssay Description:Excerpt from MH0882340 application (Dr. James Morris, Clemson University) Trypanosoma brucei, the digenic protozoan parasite that causes African slee...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46732(cid_25241618 | 2-(4-chlorophenyl)-5-fluoranyl-1,2-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPhosphomannomutase 2(Human)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM46732(cid_25241618 | 2-(4-chlorophenyl)-5-fluoranyl-1,2-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human purified PMM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM46732(cid_25241618 | 2-(4-chlorophenyl)-5-fluoranyl-1,2-...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant MIF tautomerase activity using 4-hydroxyphenylpyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed