BDBM466897 US10800767, Example 37

SMILES Cn1nc(Oc2c(Cl)cc(NC(=O)c3noc(=O)[nH]3)cc2Cl)cc(c1=O)C(C)(C)O

InChI Key InChIKey=MSDWHBYJZBEWSU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466897   

TargetThyroid hormone receptor beta(Human)
Terns

US Patent
LigandPNGBDBM466897(US10800767, Example 37)
Affinity DataEC50:  34.5nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetThyroid hormone receptor alpha(Human)
Terns

US Patent
LigandPNGBDBM466897(US10800767, Example 37)
Affinity DataEC50:  212nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent