BDBM466864 US10800767, Example 7

SMILES CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)-c2cc(=O)[nH]o2)nn(C)c1=O

InChI Key InChIKey=IWVZGLQZOTUBMN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466864   

TargetThyroid hormone receptor beta(Human)
Terns

US Patent
LigandPNGBDBM466864(US10800767, Example 7)
Affinity DataEC50:  60.9nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetThyroid hormone receptor alpha(Human)
Terns

US Patent
LigandPNGBDBM466864(US10800767, Example 7)
Affinity DataEC50:  473nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent