BDBM466859 US10800767, Example 3-P1

SMILES CC(C)c1cc(Oc2c(Cl)cc(N[C@@H](C)c3noc(=O)[nH]3)cc2Cl)nn(C)c1=O

InChI Key InChIKey=NMQHHLWLAVRNJY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466859   

TargetThyroid hormone receptor alpha(Human)
Terns

US Patent
LigandPNGBDBM466859(US10800767, Example 3-P1)
Affinity DataEC50:  75.9nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

TargetThyroid hormone receptor beta(Human)
Terns

US Patent
LigandPNGBDBM466859(US10800767, Example 3-P1)
Affinity DataEC50:  277nMAssay Description:LanthaScreen TR-FRET Thyroid Receptor alpha Coactivator Assay kit (ThermoFisher) and LanthaScreen TR-FRET Thyroid Receptor beta Coactivator Assay kit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent