BDBM466508 US10800725, Compound 16

SMILES CCC1=C(O)C(CC)(CC)C(=O)C(C(=O)CCc2ccccc2)=C1O

InChI Key InChIKey=UICDYZNJGOHHIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 466508   

TargetDNA-directed RNA polymerase subunit alpha(Escherichia coli (strain K12))
TBA

US Patent
LigandPNGBDBM466508(US10800725, Compound 16)
Affinity DataIC50: 4.00E+5nMAssay Description:Fluorescence-detected RNA polymerase assays with E. coli RNA polymerase were performed by a modification of the procedure of Kuhlman et al., 2004 [Ku...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
TBA

US Patent
LigandPNGBDBM466508(US10800725, Compound 16)
Affinity DataIC50: 4.00E+5nMAssay Description:Fluorescence-detected RNA polymerase assays with M. tuberculosis RNA polymerase were performed as in Example 21.1, using reaction mixtures containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent

TargetDNA-directed RNA polymerase subunit alpha(Staphylococcus aureus subsp. aureus N315)
TBA

US Patent
LigandPNGBDBM466508(US10800725, Compound 16)
Affinity DataIC50: 4.00E+5nMAssay Description:Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 21.1, using reaction mixtures containing (20 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
Go to US Patent