BDBM46646 2-(5-morpholin-4-ylsulfonyl-2-pyrrolidin-1-yl-phenyl)-1,2-benzothiazol-3-one::2-(5-morpholin-4-ylsulfonyl-2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-one::2-(5-morpholinosulfonyl-2-pyrrolidino-phenyl)-1,2-benzothiazol-3-one::2-[5-(4-morpholinylsulfonyl)-2-(1-pyrrolidinyl)phenyl]-1,2-benzothiazol-3-one::MLS-0069818.0001::cid_2327938

SMILES O=c1n(sc2ccccc12)-c1cc(ccc1N1CCCC1)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=NQBINQNEBDVFFF-UHFFFAOYSA-N

Data  8 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 46646   

LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataEC50:  470nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataIC50: 3.45E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataEC50:  2.26E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetPhosphomannomutase 2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataIC50: 2.98E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetPhosphoethanolamine/phosphocholine phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataIC50: 1.07E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataIC50: 7.51E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataEC50:  3.68E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataEC50:  3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2011
Entry Details
PCBioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataIC50: 1.10E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2012
Entry Details
PCBioAssay
TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of phosphomannose isomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetPhosphomannomutase 2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PMM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetPhosphoethanolamine/phosphocholine phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46646(cid_2327938 | 2-[5-(4-morpholinylsulfonyl)-2-(1-py...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of PHOSPHO1 phosphoethanolamine activity (unknown origin) assessed as amount of inorganic phosphate release after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed