BDBM465377 US10793567, Compound 12::US11225479, Compound 12

SMILES Cc1cc2CN(Cc2cn1)C(=O)Nc1nc(ccc1N)-c1cccnc1

InChI Key InChIKey=STZWFLUYGWSRNN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 465377   

TargetHistone deacetylase 2(Human)
Rodin Therapeutics

US Patent
LigandPNGBDBM465377(US10793567, Compound 12 | US11225479, Compound 12)
Affinity DataIC50: 1.50E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Rodin Therapeutics

US Patent
LigandPNGBDBM465377(US10793567, Compound 12 | US11225479, Compound 12)
Affinity DataIC50: 1.50E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Rodin Therapeutics

US Patent
LigandPNGBDBM465377(US10793567, Compound 12 | US11225479, Compound 12)
Affinity DataIC50: 2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Rodin Therapeutics

US Patent
LigandPNGBDBM465377(US10793567, Compound 12 | US11225479, Compound 12)
Affinity DataIC50: 2.75E+3nMAssay Description:The following describes an assay protocol for measuring the deacetylation of a peptide substrate by the enzymes HDAC2 or HDAC1. Enzyme, substrate, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2022
Entry Details
Go to US Patent