BDBM465267 US10793564, Compound 56::US11419869, Compound 56::US11560376, Compound 56::US20230271960, Compound 56

SMILES Cc1ccc(OCCN(CCCCc2ccc3CCCNc3n2)CC[C@H](Nc2nc(C)nc3cc(F)ccc23)C(O)=O)cn1

InChI Key InChIKey=YSEJUMFQVIBKKC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 465267   

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandPNGBDBM465267(US10793564, Compound 56 | US11560376, Compound 56 ...)
Affinity DataIC50: 50nMAssay Description:Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
Go to US Patent

TargetIntegrin alpha-5/beta-6(Human)
Pliant Therapeutics

US Patent
LigandPNGBDBM465267(US10793564, Compound 56 | US11560376, Compound 56 ...)
Affinity DataIC50: 50nMAssay Description:Microplates were coated with recombinant human integrin αVβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandPNGBDBM465267(US10793564, Compound 56 | US11560376, Compound 56 ...)
Affinity DataIC50: 50nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandPNGBDBM465267(US10793564, Compound 56 | US11560376, Compound 56 ...)
Affinity DataIC50: 50nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 μg/mL) in PBS (100 μL/well 25° C., overnight). The coating soluti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent