BDBM4650 Anilinoquinazoline deriv. 33::N-(2-Fluoro-5-hydroxy-4-methylphenyl)-6-methoxy-7-methoxyacetamido-4-quinazolinylamine hydrochloride::N-{4-[(2-fluoro-5-hydroxy-4-methylphenyl)amino]-6-methoxyquinazolin-7-yl}-2-methoxyacetamide

SMILES COCC(=O)Nc1cc2ncnc(Nc3cc(O)c(C)cc3F)c2cc1OC

InChI Key InChIKey=SGKBYSBTZYZOJQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4650   

LigandPNGBDBM4650(N-{4-[(2-fluoro-5-hydroxy-4-methylphenyl)amino]-6-...)
Affinity DataIC50: 300nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed
LigandPNGBDBM4650(N-{4-[(2-fluoro-5-hydroxy-4-methylphenyl)amino]-6-...)
Affinity DataIC50: 300nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Astrazeneca

LigandPNGBDBM4650(N-{4-[(2-fluoro-5-hydroxy-4-methylphenyl)amino]-6-...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed