BDBM464588 CIS-1-(Cyclobutyl-methyl)-8-dimethylamino-3-[2-[2-[2-(2-methoxy-ethoxy)- ethoxy]-ethoxy]-ethyl]-8-phenyl-1,3-diazaspiro[4.5]decan-2-one::US10793556, Example SC_4008

SMILES COCCOCCOCCOCCN1C[C@]2(CC[C@@](CC2)(N(C)C)c2ccccc2)N(CC2CCC2)C1=O

InChI Key InChIKey=UMMKSWWYJDBWCX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 464588   

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM464588(US10793556, Example SC_4008 | CIS-1-(Cyclobutyl-me...)
Affinity DataKi:  7.30nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
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TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM464588(US10793556, Example SC_4008 | CIS-1-(Cyclobutyl-me...)
Affinity DataKi:  69.8nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2021
Entry Details
Go to US Patent