BDBM464220 US10787450, Example 100::propyl 3-(4-(1H- pyrazol-4-yl)phenyl)- 1-(3-methoxybenzyl)- 2-oxo-1,3,8- triazaspiro[4.5]decane- 8-carboxylate

SMILES CCCOC(=O)N1CCC2(CN(C(=O)N2Cc2cccc(OC)c2)c2ccc(cc2)-c2cn[nH]c2)CC1

InChI Key InChIKey=OSITVTQQWBXUIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464220   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM464220(propyl 3-(4-(1H- pyrazol-4-yl)phenyl)- 1-(3-methox...)
Affinity DataIC50: 3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
US Patent