BDBM464123 US10787436, Compound I-70

SMILES CN1CCN(CC1)c1cc(ccn1)-c1nc(Nc2cccc(NC(=O)c3ccc(NC(=O)C=C)cc3)c2)ncc1Cl

InChI Key InChIKey=WAXFETFFIWFJFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464123   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM464123(US10787436, Compound I-70)
Affinity DataIC50: 100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent