BDBM464121 US10787436, Compound I-68

SMILES CN(C)C\C=C/C(=O)Nc1ccc(NC(=O)c2cccc(Nc3ncc(Cl)c(n3)-c3c[nH]c4ccccc34)c2)cc1

InChI Key InChIKey=PVQGKFOUZXHLJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464121   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM464121(US10787436, Compound I-68)
Affinity DataIC50: 100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent