BDBM464113 US10787436, Compound I-57

SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N(C)c1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1

InChI Key InChIKey=WCEPKSPQLQRWAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464113   

TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM464113(US10787436, Compound I-57)
Affinity DataIC50: 100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2021
Entry Details
Go to US Patent