BDBM4641 Anilinoquinazoline deriv. 24::N-(4-Chloro-2-fluorophenyl)-6-methoxy-7-[2-[2-(4-morpholinyl)-ethoxy]ethoxy]-4-quinazolinylamine hydrochloride::N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{2-[2-(morpholin-4-yl)ethoxy]ethoxy}quinazolin-4-amine

SMILES COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCOCCN1CCOCC1

InChI Key InChIKey=SPRJHDMLXZXXRJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4641   

LigandPNGBDBM4641(N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{2-[2-(mor...)
Affinity DataIC50: 60nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed
LigandPNGBDBM4641(N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{2-[2-(mor...)
Affinity DataIC50: 500nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Astrazeneca

LigandPNGBDBM4641(N-(4-chloro-2-fluorophenyl)-6-methoxy-7-{2-[2-(mor...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2005
Entry Details Article
PubMed