BDBM463479 3-(3,4-Dihydroquinolin-1(2H)-yl)-2-phenylquinoxaline-6-carboxylic acid::US10781185, Example 40::US11459307, Example 40

SMILES OC(=O)c1ccc2nc(-c3ccccc3)c(nc2c1)N1CCCc2ccccc12

InChI Key InChIKey=QNTAFDGTGJMGAA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 463479   

LigandPNGBDBM463479(3-(3,4-Dihydroquinolin-1(2H)-yl)-2-phenylquinoxali...)
Affinity DataIC50: 1.00E+3nMAssay Description:Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
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LigandPNGBDBM463479(3-(3,4-Dihydroquinolin-1(2H)-yl)-2-phenylquinoxali...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
Go to US Patent

LigandPNGBDBM463479(3-(3,4-Dihydroquinolin-1(2H)-yl)-2-phenylquinoxali...)
Affinity DataIC50: 1.00E+4nMAssay Description:Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

LigandPNGBDBM463479(3-(3,4-Dihydroquinolin-1(2H)-yl)-2-phenylquinoxali...)
Affinity DataIC50: 1.00E+4nMAssay Description:The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent