BDBM462396 US10780078, Compound DD 277

SMILES C[C@@H](Cc1ccsc1)NC(=O)NCC1(Cc2ccccc2C1)N(C)C

InChI Key InChIKey=FUCRJYKIXJXVCV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 462396   

TargetMu-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM462396(US10780078, Compound DD 277)
Affinity DataKi:  500nMAssay Description:This study supports a structure-based approach for GPCR ligand discovery. These new chemotypes may stabilize receptor conformations not explored prev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2021
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
University of California

US Patent
LigandPNGBDBM462396(US10780078, Compound DD 277)
Affinity DataKi:  700nMAssay Description:This study supports a structure-based approach for GPCR ligand discovery. These new chemotypes may stabilize receptor conformations not explored prev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2021
Entry Details
Go to US Patent

TargetDelta-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM462396(US10780078, Compound DD 277)
Affinity DataKi:  8.40E+3nMAssay Description:This study supports a structure-based approach for GPCR ligand discovery. These new chemotypes may stabilize receptor conformations not explored prev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2021
Entry Details
Go to US Patent