BDBM4623 Anilinoquinazoline deriv. 6::N-(2-fluoro-4-iodophenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES COc1cc2ncnc(Nc3ccc(I)cc3F)c2cc1OC

InChI Key InChIKey=KEARPGNXFPCRCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4623   

LigandPNGBDBM4623(N-(2-fluoro-4-iodophenyl)-6,7-dimethoxyquinazolin-...)
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit VEGF-R RTK activity. The compounds were incubated with enzyme 20 min at room...More data for this Ligand-Target Pair
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Date in BDB:
5/24/2005
Entry Details Article
PubMed