BDBM462203 US10766884, Example F21

SMILES C[C@H](O)C(=O)N1CC[C@@H](Nc2ncc(Cl)c(n2)-c2cc(F)c3ncn(c3c2)C(C)(C)C)[C@H](O)C1

InChI Key InChIKey=QSWXQGNVXUPASL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 462203   

LigandPNGBDBM462203(US10766884, Example F21)
Affinity DataKi:  0.400nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

LigandPNGBDBM462203(US10766884, Example F21)
Affinity DataKi:  7.70nMAssay Description:CDK6/Cyclin D3: The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent