BDBM462092 US10766884, Example A09

SMILES CC5(C)CCc4nc3c(F)cc(c2nc(N[C@H]1CCN(S(C)(=O)=O)C[C@@H]1O)ncc2Cl)cc3n45

InChI Key InChIKey=WPISIVVUJBUBHG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 462092   

LigandPNGBDBM462092(US10766884, Example A09)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent

LigandPNGBDBM462092(US10766884, Example A09)
Affinity DataKi:  1.40nMAssay Description:CDK6/Cyclin D3: The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/26/2021
Entry Details
Go to US Patent