BDBM462078 N-((3-chloro-1-(4- (trifluoromethyl)phenyl)-1H- pyrazol-4-yl)methyl)-2-(4- fluorophenylsulfonyl) cyclopentanecarboxamide (Enantiomer 2)::US10766878, Example 42

SMILES Fc1ccc(cc1)S(=O)(=O)C1CCCC1C(=O)NCc1cn(nc1Cl)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=LGVSQHZAKUBGAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 462078   

LigandPNGBDBM462078(N-((3-chloro-1-(4- (trifluoromethyl)phenyl)-1H- py...)
Affinity DataIC50: 45.5nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462078(N-((3-chloro-1-(4- (trifluoromethyl)phenyl)-1H- py...)
Affinity DataIC50: 45.5nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent