BDBM462070 2-(4-fluorophenylsulfonyl)-N-((3- methoxy-1-(6- (trifluoromethyl)pyridin-3-yl)-1H- pyrazol-4-yl)methyl)-1- methylcyclopentanecarboxamide (Enantiomer 1)::US10766878, Example 34::US10766878, Example 35::US10766878, Example 36

SMILES COc1nn(cc1CNC(=O)C1(C)CCCC1S(=O)(=O)c1ccc(F)cc1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=HRAPYHSCUKKKMN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 462070   

LigandPNGBDBM462070(US10766878, Example 34 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 33.1nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462070(US10766878, Example 34 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 33.1nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462070(US10766878, Example 34 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 62.2nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462070(US10766878, Example 34 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 199nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent