BDBM462061 2-(4-fluorophenylsulfonyl)-N-((3- (trifluoromethyl)-1-(6- (trifluoromethyl)pyridin-3-yl)-1H- pyrazol-4-yl)methyl) cyclobutanecarboxamide (Enantiomer 2)::US10766878, Example 25::US10766878, Example 26

SMILES Fc1ccc(cc1)S(=O)(=O)C1CCC1C(=O)NCc1cn(nc1C(F)(F)F)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=CERUYKDYVULSDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 462061   

LigandPNGBDBM462061(US10766878, Example 25 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 90.2nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462061(US10766878, Example 25 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 192nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent