BDBM462058 2-(4-fluorophenylsulfonyl)-N-(3- methoxy-1-(4- (trifluoromethyl)phenyl)-1H- pyrazol-4-yl)methyl)-2- methylcyclobutanecarboxamide (Enantiomer 1)::US10766878, Example 22::US10766878, Example 23

SMILES COc1nn(cc1CNC(=O)C1CCC1(C)S(=O)(=O)c1ccc(F)cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=VBECZLUYZDGVPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 462058   

LigandPNGBDBM462058(US10766878, Example 22 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 38nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462058(US10766878, Example 22 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 38nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462058(US10766878, Example 22 | 2-(4-fluorophenylsulfonyl...)
Affinity DataIC50: 71.7nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent