BDBM462056 (1S,2S)-N-((3-(difluoromethyl)-1-(6- (trifluoromethyl)pyridin-3-yl)-1H- pyrazol-4-yl)methyl)-2-((4- fluorophenyl)sulfonyl) cyclobutanecarboxamide::US10766878, Example 20

SMILES FC(F)c1nn(cc1CNC(=O)[C@@H]1CC[C@@H]1S(=O)(=O)c1ccc(F)cc1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=TVZRIJSXZCQZFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462056   

LigandPNGBDBM462056((1S,2S)-N-((3-(difluoromethyl)-1-(6- (trifluoromet...)
Affinity DataIC50: 98.4nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent