BDBM462049 N-((1R,2S)-2-((4- fluorophenyl)sulfonyl)cyclobutyl)- 2-(3-methoxy-1-(6- (trifluoromethyl)pyridin-3-yl)-1H- pyrazol-4-yl)acetamide::US10766878, Example 13

SMILES COc1nn(cc1CC(=O)N[C@@H]1CC[C@@H]1S(=O)(=O)c1ccc(F)cc1)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=MJYWLKTXRPVKEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 462049   

LigandPNGBDBM462049(N-((1R,2S)-2-((4- fluorophenyl)sulfonyl)cyclobutyl...)
Affinity DataIC50: 18.5nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462049(N-((1R,2S)-2-((4- fluorophenyl)sulfonyl)cyclobutyl...)
Affinity DataIC50: 18.5nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent