BDBM462046 2-(1-(4-(difluoromethyl)phenyl)-3- methoxy-1H-pyrazol-4-yl)-N- ((1R,2S)-2-(4- fluorophenylsulfonyl)cyclobutyl) acetamide::US10766878, Example 10

SMILES COc1nn(cc1CC(=O)N[C@@H]1CC[C@@H]1S(=O)(=O)c1ccc(F)cc1)-c1ccc(cc1)C(F)F

InChI Key InChIKey=RYUCFDWWFHXUHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 462046   

LigandPNGBDBM462046(2-(1-(4-(difluoromethyl)phenyl)-3- methoxy-1H-pyra...)
Affinity DataIC50: 43.6nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
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Date in BDB:
4/26/2021
Entry Details
US Patent