BDBM462045 2-(3-(difluoromethyl)-1-(2- (trifluoromethyl)pyrimidin-5-yl)- 1H-pyrazol-4-yl)-N-((1R,2S)-2-(4- fluorophenylsulfonyl) cyclobutyl)acetamide::US10766878, Example 9

SMILES FC(F)c1nn(cc1CC(=O)N[C@@H]1CC[C@@H]1S(=O)(=O)c1ccc(F)cc1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=VTRQWSXLXNAIDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 462045   

LigandPNGBDBM462045(2-(3-(difluoromethyl)-1-(2- (trifluoromethyl)pyrim...)
Affinity DataIC50: 35.2nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462045(2-(3-(difluoromethyl)-1-(2- (trifluoromethyl)pyrim...)
Affinity DataIC50: 35.2nMAssay Description:IC50 values (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent