BDBM461931 4-((1-(3-chloro-2-fluoro-6-(trifluoromethyl)benzyl)-4-fluoropiperidin-4-yl)methoxy)-N-(cyclopropanesulfonimidoyl)-5-cyclopropyl-2-fluorobenzamide::US10766858, Example 19

SMILES Fc1cc(OCC2(F)CCN(Cc3cc(cc(Cl)c3F)C(F)(F)F)CC2)c(cc1C(=O)NS(=N)(=O)C1CC1)C1CC1

InChI Key InChIKey=CDSAYZNEQFJOKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461931   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461931(4-((1-(3-chloro-2-fluoro-6-(trifluoromethyl)benzyl...)
Affinity DataIC50: 182nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent