BDBM461929 N-(cyclopropanesulfonimidoyl)-5-cyclopropyl-4-(((R)-1-(2,6-dichlorobenzyl)piperidin-3-yl)oxy)-2-fluorobenzamide::US10766858, Example 17

SMILES Fc1cc(O[C@@H]2CCCN(Cc3c(Cl)cccc3Cl)C2)c(cc1C(=O)NS(=N)(=O)C1CC1)C1CC1

InChI Key InChIKey=VMPLHOYLPOQSCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461929   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461929(N-(cyclopropanesulfonimidoyl)-5-cyclopropyl-4-(((R...)
Affinity DataIC50: 2.29E+3nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent