BDBM461928 5-chloro-4-((5-chloro-6-isopropoxypyridin-3-yl)oxy)-N-(cyclopropanesulfonimidoyl)-2-fluorobenzamide::US10766858, Example 16

SMILES CC(C)Oc1ncc(Oc2cc(F)c(cc2Cl)C(=O)NS(=N)(=O)C2CC2)cc1Cl

InChI Key InChIKey=DMBOCHHLWCKOKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461928   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461928(5-chloro-4-((5-chloro-6-isopropoxypyridin-3-yl)oxy...)
Affinity DataIC50: 18.1nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent