BDBM461927 4-((5-chloro-6-isopropoxypyridin-3-yl)oxy)-N-(cyclopropanesulfonimidoyl)-2-fluoro-5-(2-methoxypyridin-3-yl)benzamide::US10766858, Example 15

SMILES COc1ncccc1-c1cc(C(=O)NS(=N)(=O)C2CC2)c(F)cc1Oc1cnc(OC(C)C)c(Cl)c1

InChI Key InChIKey=APUUUPPKNJSSOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461927   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461927(4-((5-chloro-6-isopropoxypyridin-3-yl)oxy)-N-(cycl...)
Affinity DataIC50: 19.8nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent