BDBM461926 5-chloro-4-((5-chloro-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)oxy)-N-(cyclopropanesulfonimidoyl)-2-fluorobenzamide::US10766858, Example 14

SMILES Fc1cc(Oc2cnc(OCC(F)(F)F)c(Cl)c2)c(Cl)cc1C(=O)NS(=N)(=O)C1CC1

InChI Key InChIKey=ODZVXWDMFJSGDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461926   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461926(5-chloro-4-((5-chloro-6-(2,2,2-trifluoroethoxy)pyr...)
Affinity DataIC50: 23.6nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
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Date in BDB:
4/26/2021
Entry Details
US Patent