BDBM461925 4-(((3r,5r,7r)-adamantan-1-yl)methoxy)-N-(azetidine-1-sulfonimidoyl)-5-cyclopropyl-2-fluorobenzamide::US10766858, Example 13

SMILES Fc1cc(OCC23CC4CC(CC(C4)C2)C3)c(cc1C(=O)NS(=N)(=O)N1CCC1)C1CC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461925   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461925(4-(((3r,5r,7r)-adamantan-1-yl)methoxy)-N-(azetidin...)
Affinity DataIC50: 80.9nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent