BDBM461924 N-(azetidine-1-sulfonimidoyl)-5-chloro-4-((5-chloro-6-(2,2,3,3-tetrafluoropropoxy)pyridin-3-yl)oxy-2-fluorobenzamide::US10766858, Example 12

SMILES FC(F)C(F)(F)COc1ncc(Oc2cc(F)c(cc2Cl)C(=O)NS(=N)(=O)N2CCC2)cc1Cl

InChI Key InChIKey=VVHUDSXHNHREGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461924   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461924(N-(azetidine-1-sulfonimidoyl)-5-chloro-4-((5-chlor...)
Affinity DataIC50: 159nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
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Date in BDB:
4/26/2021
Entry Details
US Patent