BDBM461923 N-(cyclopropanesulfonimidoyl)-5-cyclopropyl-2-fluoro-4-((3-fluoro-5-(trifluoromethyl)phenoxy)methyl)benzamide::US10766858, Example 11

SMILES Fc1cc(OCc2cc(F)c(cc2C2CC2)C(=O)NS(=N)(=O)C2CC2)cc(c1)C(F)(F)F

InChI Key InChIKey=MCBHRKDBKVKECZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461923   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461923(N-(cyclopropanesulfonimidoyl)-5-cyclopropyl-2-fluo...)
Affinity DataIC50: 14.2nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent