BDBM461922 4-((3-chloro-5-(trifluoromethoxy)phenoxy)methyl)-N-(cyclopropanesulfonimidoyl)-5-cyclopropyl-2-fluorobenzamide::US10766858, Example 10

SMILES Fc1cc(COc2cc(Cl)cc(OC(F)(F)F)c2)c(cc1C(=O)NS(=N)(=O)C1CC1)C1CC1

InChI Key InChIKey=CJESGCORRBGAMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461922   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461922(4-((3-chloro-5-(trifluoromethoxy)phenoxy)methyl)-N...)
Affinity DataIC50: 8.67nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent