BDBM461920 4-(3-chloro-4-(trifluoromethoxy)phenoxy)-N-(cyclopropanesulfonimidoyl)-2,5-difluorobenzamide::US10766858, Example 8

SMILES Fc1cc(C(=O)NS(=N)(=O)C2CC2)c(F)cc1Oc1ccc(OC(F)(F)F)c(Cl)c1

InChI Key InChIKey=KEWVLEZAUQKXKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461920   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461920(4-(3-chloro-4-(trifluoromethoxy)phenoxy)-N-(cyclop...)
Affinity DataIC50: 238nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent