BDBM461916 4-((adamantan-1-yl)methoxy)-5-chloro-N-(cyclopropanesulfonimidoyl)-2-fluorobenzamide::US10766858, Example 4::US10766858, Example 6

SMILES NC(=O)c1cc(Cl)c(OCC23CC4CC(CC(C4)C2)C3)cc1F

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 461916   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461916(US10766858, Example 6 | 4-((adamantan-1-yl)methoxy...)
Affinity DataIC50: 112nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461916(US10766858, Example 6 | 4-((adamantan-1-yl)methoxy...)
Affinity DataIC50: 1.43E+3nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent