BDBM461914 4-((4-chloro-2-cyanophenoxy)methyl)-N-(cyclopropanesulfonimidoyl)-5-cyclopropyl-2-fluorobenzamide::US10766858, Example 2

SMILES NC(=O)c1cc(C2CC2)c(COc2ccc(Cl)cc2C#N)cc1F

InChI Key InChIKey=SRGIUWXUCPXZMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461914   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM461914(4-((4-chloro-2-cyanophenoxy)methyl)-N-(cyclopropan...)
Affinity DataIC50: 2.61E+3nMAssay Description:isolated from cells that heterologously express hNav1.7 and the β1 subunit Preparation of membranes containing recombinantly expressed sodium ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent