BDBM461896 US10774085, Example 91

SMILES COc1ccc(F)cc1[C@H]1CCCN1c1ccn2ncc(NC(=O)N3CCCC(O)C3)c2n1

InChI Key InChIKey=RGIQATAASXNYCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 461896   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandPNGBDBM461896(US10774085, Example 91)
Affinity DataIC50: 10.2nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2021
Entry Details
Go to US Patent