BDBM4612 1,6-naphthyridine deriv. 14::1-[7-amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-3-ethylurea::N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridin-2-yl]-N-ethylurea

SMILES CCNC(=O)Nc1nc2cc(N)ncc2cc1-c1cc(OC)cc(OC)c1

InChI Key InChIKey=ANRWHDLTBMMQJD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4612   

TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM4612(N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridi...)
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM4612(N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridi...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM4612(N-[7-Amino-3-(3,5-dimethoxyphenyl)-1,6-naphthyridi...)
Affinity DataIC50: 5.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed